Meropenem Induced Anaphylactic Shock in a Newborn and Review Of Literature Meropenem

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Meropenem Induced Anaphylactic Shock in a Newborn and Review Of Literature

All drugs have the potential cause to side effects and anaphylaxis.The bioavailability of the drugs is different in newborns. Therefore has the tolerability and efficacy of the medicationsin the newborn period more importance. Meropenem is a broad-spectrum antibiotic used to treat a wide variety of infections. We describe here a neonate who developed anaphylactic shock after use of intravenous ...

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Meropenem pharmacokinetics in the newborn.

We studied meropenem in 23 pre-term (gestational age, 29 to 36 weeks) and 15 full-term (gestational age, 37 to 42 weeks) neonates. Meropenem doses of 10, 20, and 40 mg/kg were administered as single doses (30-min intravenous infusion) on a random basis. Blood was obtained for determining the meropenem concentration nine times. Each child required other antimicrobials for proven/suspected bacter...

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Meropenem-induced myoclonus: A case report

A 61-year-old woman was seen at the intensive care unit because of myoclonic status. Her medical history included arterial hypertension, dyslipidemia and diabetes. In the previous year she had been hospitalized because of dilated cardiomyopathy (ejection fraction 21%) and non-sustained ventricular tachycardia. At that time she was managed with an implantable cardiac defibrillator. On this admis...

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Clinical Pharmacology of Meropenem in Neonates: Effects and Pharmacokinetics

     Meropenem, a carbapenem antibiotic, has a broad-spectrum activity and is active against Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influencae, Moraxella catarrhalis, gram-negative enteric bacilli as Escherichia coli, Klebsiella, Enterobacter, Serratia and Pseudomonas aeruginosa. Meropenem has excellent penetration in body tissues and in cerebrospinal fluid (in the presenc...

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Use of meropenem in the treatment of serious infections in children: review of the current literature.

Meropenem is a new beta-lactam carbapenem antibiotic that appears to be promising in the treatment of hospitalized infants and children with serious infections. It has broad-spectrum activity against microorganisms, including most of the major aerobic (gram-negative and gram-positive) and anaerobic pathogens that cause serious bacterial infections in neonates and children. In addition, its phar...

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ژورنال

عنوان ژورنال: Academic Journal of Pediatrics & Neonatology

سال: 2016

ISSN: 2474-7521

DOI: 10.19080/ajpn.2016.02.555582